Homo sapiens has evolved to live comfortably on just ten percent of the surface of this planet, Earth — seventy percent of it is ocean, ten percent too hot, and ten percent too cold. Humans in their present form will not colonize the solar system, let alone the galaxy. Machines may. They could incorporate human consciousness, or be pure AI, separate from (but created by) human intelligence. You might be interested in my articles Populate the planets? Really? and What space aliens look like.